Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia

Proxy phenotypes allow for the utilization of genetic data from large population cohorts to analyze late-onset diseases by using parental diagnoses as a proxy for genetic disease risk. Proxy phenotypes based on parental diagnosis status have been used in previous studies to identify common variants...

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Detalles Bibliográficos
Autores principales: Wightman, Douglas P., Savage, Jeanne E., de Leeuw, Christiaan A., Jansen, Iris E., Posthuma, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905079/
https://www.ncbi.nlm.nih.gov/pubmed/36750708
http://dx.doi.org/10.1038/s41598-023-29108-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905079/
https://www.ncbi.nlm.nih.gov/pubmed/36750708
http://dx.doi.org/10.1038/s41598-023-29108-8

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