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Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture

Hip fractures in nonagenarians is one of the great challenges for patients of this age, the family and the larger society. The purpose of this study was to investigate the risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture. 199 Eligible patients were enrolled. Co...

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Autores principales: Zhao, Shengjie, Sun, Tiansheng, Zhang, Jianzheng, Chen, Xiaobin, Wang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905086/
https://www.ncbi.nlm.nih.gov/pubmed/36750657
http://dx.doi.org/10.1038/s41598-023-27829-4
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author Zhao, Shengjie
Sun, Tiansheng
Zhang, Jianzheng
Chen, Xiaobin
Wang, Xiaowei
author_facet Zhao, Shengjie
Sun, Tiansheng
Zhang, Jianzheng
Chen, Xiaobin
Wang, Xiaowei
author_sort Zhao, Shengjie
collection PubMed
description Hip fractures in nonagenarians is one of the great challenges for patients of this age, the family and the larger society. The purpose of this study was to investigate the risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture. 199 Eligible patients were enrolled. Confusion Assessment Method (CAM) were used to identify the delirium. Logistic regressions were used to investigate the effect of 18 pre-existing conditions on postoperative delirium. Prognosis of postoperative delirium in nonagenarians with hip fracture were also be evaluated. The results indicated the following: (1) the prevalence of postoperative delirium among nonagenarians with hip fracture was 28.1% (56 of 199); (2) coexisting disease ≥ 4 (OR = 5.355, 95% CI = 1.394–9.074, P = 0.007), longer admission to operating time (OR = 1.514, 95% CI = 1.247–1.837, P = 0.000), and general anesthesia (OR = 2.086, 95% CI = 1.804–7.968, P = 0.032) were independent risk factors for postoperative delirium in nonagenarians with hip fracture; (3) nonagenarians with postoperative delirium had a predominantly high burden of perioperative complications, long length of stay, and postoperative mortality at 30 days follow-up and 1 year follow-up than the patients without postoperative delirium. The results could enable clinicians to improve outcome after operation in nonagenarians with hip fracture.
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spelling pubmed-99050862023-02-08 Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture Zhao, Shengjie Sun, Tiansheng Zhang, Jianzheng Chen, Xiaobin Wang, Xiaowei Sci Rep Article Hip fractures in nonagenarians is one of the great challenges for patients of this age, the family and the larger society. The purpose of this study was to investigate the risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture. 199 Eligible patients were enrolled. Confusion Assessment Method (CAM) were used to identify the delirium. Logistic regressions were used to investigate the effect of 18 pre-existing conditions on postoperative delirium. Prognosis of postoperative delirium in nonagenarians with hip fracture were also be evaluated. The results indicated the following: (1) the prevalence of postoperative delirium among nonagenarians with hip fracture was 28.1% (56 of 199); (2) coexisting disease ≥ 4 (OR = 5.355, 95% CI = 1.394–9.074, P = 0.007), longer admission to operating time (OR = 1.514, 95% CI = 1.247–1.837, P = 0.000), and general anesthesia (OR = 2.086, 95% CI = 1.804–7.968, P = 0.032) were independent risk factors for postoperative delirium in nonagenarians with hip fracture; (3) nonagenarians with postoperative delirium had a predominantly high burden of perioperative complications, long length of stay, and postoperative mortality at 30 days follow-up and 1 year follow-up than the patients without postoperative delirium. The results could enable clinicians to improve outcome after operation in nonagenarians with hip fracture. Nature Publishing Group UK 2023-02-07 /pmc/articles/PMC9905086/ /pubmed/36750657 http://dx.doi.org/10.1038/s41598-023-27829-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhao, Shengjie
Sun, Tiansheng
Zhang, Jianzheng
Chen, Xiaobin
Wang, Xiaowei
Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
title Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
title_full Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
title_fullStr Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
title_full_unstemmed Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
title_short Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
title_sort risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905086/
https://www.ncbi.nlm.nih.gov/pubmed/36750657
http://dx.doi.org/10.1038/s41598-023-27829-4
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