Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease

INTRODUCTION: Diabetic kidney disease (DKD) is one of the complications of diabetes; however, the pathogenesis is not yet clear. A recent study has shown that senescence is associated with the course of DKD. In the present study, we explored whether senescent renal tubular cells promote renal tubulo...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Yin, Ling, Chen, Rongyu, Tan, Wanlin, Liang, Luqun, Xiang, Jiayi, Zhang, Huifang, Zhou, Xingcheng, Deng, Huaqing, Guo, Bing, Wang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905119/
https://www.ncbi.nlm.nih.gov/pubmed/36760880
http://dx.doi.org/10.3389/fmed.2022.1018298

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