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Inclusion of cancer-associated fibroblasts in drug screening assays to evaluate pancreatic cancer resistance to therapeutic drugs

Pancreatic ductal adenocarcinoma (PDAC) is characterised by a pro-inflammatory stroma and multi-faceted microenvironment that promotes and maintains tumorigenesis. However, the models used to test new and emerging therapies for PDAC have not increased in complexity to keep pace with our understandin...

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Detalles Bibliográficos
Autores principales: Brumskill, Sarah, Barrera, Lawrence N., Calcraft, Peter, Phillips, Caroline, Costello, Eithne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905179/
https://www.ncbi.nlm.nih.gov/pubmed/34865180
http://dx.doi.org/10.1007/s13105-021-00857-2