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Inclusion of cancer-associated fibroblasts in drug screening assays to evaluate pancreatic cancer resistance to therapeutic drugs
Pancreatic ductal adenocarcinoma (PDAC) is characterised by a pro-inflammatory stroma and multi-faceted microenvironment that promotes and maintains tumorigenesis. However, the models used to test new and emerging therapies for PDAC have not increased in complexity to keep pace with our understandin...
Autores principales: | Brumskill, Sarah, Barrera, Lawrence N., Calcraft, Peter, Phillips, Caroline, Costello, Eithne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905179/ https://www.ncbi.nlm.nih.gov/pubmed/34865180 http://dx.doi.org/10.1007/s13105-021-00857-2 |
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