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The role of microRNAs in the modulation of cancer-associated fibroblasts activity during pancreatic cancer pathogenesis
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest of the common cancers. A major hallmark of PDAC is an abundant and dense fibrotic stroma, the result of a disproportionate deposition of extracellular matrix (ECM) proteins. Cancer-associated fibroblasts (CAFs) are the main mediators of PDAC d...
Autores principales: | Barrera, Lawrence N., Ridley, P. Matthew, Bermejo-Rodriguez, Camino, Costello, Eithne, Perez-Mancera, Pedro A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905185/ https://www.ncbi.nlm.nih.gov/pubmed/35767180 http://dx.doi.org/10.1007/s13105-022-00899-0 |
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