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Lipoxin A4 attenuated dexamethasone-induced muscle atrophy via activation of PGC-1α/Nrf2/TFAM pathway

Prolonged dexamethasone (DEX) administration causes skeletal muscle atrophy through induction of both oxidative stress and mitochondrial dysfunction. Lipoxin A4 (LXA4) is a recognized antioxidant but its effect against DEX-induced muscle atrophy has not been studied yet. This study aimed to assess t...

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Detalles Bibliográficos
Autores principales:	Rizk, Fatma H., Soliman, Nema A., Kashef, Shaimaa M., Elsaadany, Amira A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905194/ https://www.ncbi.nlm.nih.gov/pubmed/36125698 http://dx.doi.org/10.1007/s13105-022-00925-1

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