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Nalmefene vs. dexmedetomidine for prevention of postoperative hyperalgesia in patients undergoing laparoscopic gynecological surgery with remifentanil infusion: A randomized double-blind controlled trial

Intraoperative remifentanil infusion may paradoxically induce post-surgical hyperalgesia. Dexmedetomidine reportedly reduces opioid-induced hyperalgesia. Nalmefene selectively reverses several side-effects of opioids without impairing analgesia. Herein, this randomized, double-blind controlled trial...

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Detalles Bibliográficos
Autores principales:	Jia, Zhen, Chen, Yi, Gao, Tianyu, Yuan, Yuan, Zheng, Yuxin, Xie, Yegong, Wang, Guolin, Yu, Yonghao, Zhang, Linlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905252/ https://www.ncbi.nlm.nih.gov/pubmed/36762101 http://dx.doi.org/10.3389/fphar.2023.1131812

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