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Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report

Mixed cryoglobulinemia refers to the serum presence of a variety of cryoglobulins, which are defined as immunoglobulins that precipitate at temperatures of < 37°C. The most common cause of mixed cryoglobulinemia is hepatitis C virus (HCV), while other infections, including hepatitis B virus (HBV)...

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Autores principales: Luo, Jiao, Liu, Cheng, Lv, Qing-Jian, He, Ting, Qiang, Xing, Li, Yi, Huang, Qi-Mi, He, Jia-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905412/
https://www.ncbi.nlm.nih.gov/pubmed/36760401
http://dx.doi.org/10.3389/fmed.2023.1014261
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author Luo, Jiao
Liu, Cheng
Lv, Qing-Jian
He, Ting
Qiang, Xing
Li, Yi
Huang, Qi-Mi
He, Jia-Lin
author_facet Luo, Jiao
Liu, Cheng
Lv, Qing-Jian
He, Ting
Qiang, Xing
Li, Yi
Huang, Qi-Mi
He, Jia-Lin
author_sort Luo, Jiao
collection PubMed
description Mixed cryoglobulinemia refers to the serum presence of a variety of cryoglobulins, which are defined as immunoglobulins that precipitate at temperatures of < 37°C. The most common cause of mixed cryoglobulinemia is hepatitis C virus (HCV), while other infections, including hepatitis B virus (HBV) and HIV infections, and lymphoproliferative and autoimmune disorders have also been associated with the disease. We reported a rare case of type II–III mixed cryoglobulinemia caused by alcoholic cirrhosis. We need to increase the awareness of and facilitate the early identification of mixed cryoglobulinemia in our clinical study when encountering a patient with liver cirrhosis combined with renal impairment so that treatment can begin early to improve the success rate of therapy and reduce the fatality rate in a potentially life-saving therapy.
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spelling pubmed-99054122023-02-08 Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report Luo, Jiao Liu, Cheng Lv, Qing-Jian He, Ting Qiang, Xing Li, Yi Huang, Qi-Mi He, Jia-Lin Front Med (Lausanne) Medicine Mixed cryoglobulinemia refers to the serum presence of a variety of cryoglobulins, which are defined as immunoglobulins that precipitate at temperatures of < 37°C. The most common cause of mixed cryoglobulinemia is hepatitis C virus (HCV), while other infections, including hepatitis B virus (HBV) and HIV infections, and lymphoproliferative and autoimmune disorders have also been associated with the disease. We reported a rare case of type II–III mixed cryoglobulinemia caused by alcoholic cirrhosis. We need to increase the awareness of and facilitate the early identification of mixed cryoglobulinemia in our clinical study when encountering a patient with liver cirrhosis combined with renal impairment so that treatment can begin early to improve the success rate of therapy and reduce the fatality rate in a potentially life-saving therapy. Frontiers Media S.A. 2023-01-25 /pmc/articles/PMC9905412/ /pubmed/36760401 http://dx.doi.org/10.3389/fmed.2023.1014261 Text en Copyright © 2023 Luo, Liu, Lv, He, Qiang, Li, Huang and He. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Luo, Jiao
Liu, Cheng
Lv, Qing-Jian
He, Ting
Qiang, Xing
Li, Yi
Huang, Qi-Mi
He, Jia-Lin
Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
title Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
title_full Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
title_fullStr Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
title_full_unstemmed Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
title_short Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
title_sort non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: a rare case report
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905412/
https://www.ncbi.nlm.nih.gov/pubmed/36760401
http://dx.doi.org/10.3389/fmed.2023.1014261
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