Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics

BACKGROUND: Sézary Syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL). In SS patients, malignant T cells are circulating through the blood and cause erythroderma. OBJECTIVE: To compare the transcriptome of single cells in blood and skin samples from a patient with a...

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Detalles Bibliográficos
Autores principales: Peiffer, Lukas, Gambichler, Thilo, Buus, Terkild B., Horny, Kai, Gravemeyer, Jan, Furtmann, Frauke, Spassova, Ivelina, Kubat, Linda, Susok, Laura, Stranzenbach, René, Srinivas, Nalini, Ødum, Niels, Becker, Jürgen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905421/
https://www.ncbi.nlm.nih.gov/pubmed/36761972
http://dx.doi.org/10.3389/fonc.2023.1090592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905421/
https://www.ncbi.nlm.nih.gov/pubmed/36761972
http://dx.doi.org/10.3389/fonc.2023.1090592

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