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Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics
BACKGROUND: Sézary Syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL). In SS patients, malignant T cells are circulating through the blood and cause erythroderma. OBJECTIVE: To compare the transcriptome of single cells in blood and skin samples from a patient with a...
Autores principales: | Peiffer, Lukas, Gambichler, Thilo, Buus, Terkild B., Horny, Kai, Gravemeyer, Jan, Furtmann, Frauke, Spassova, Ivelina, Kubat, Linda, Susok, Laura, Stranzenbach, René, Srinivas, Nalini, Ødum, Niels, Becker, Jürgen C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905421/ https://www.ncbi.nlm.nih.gov/pubmed/36761972 http://dx.doi.org/10.3389/fonc.2023.1090592 |
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