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A single point mutation expands the applicability of ostreolysin A6 in biomedicine

An aegerolysin protein ostreolysin A6 (OlyA6) binds to cholesterol-complexed sphingomyelin and can be used for specific labelling of lipid rafts. In addition, OlyA6 interacts with even higher affinity with ceramide phosphoethanolamine (CPE), a sphingolipid that dominates in invertebrate cell membran...

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Detalles Bibliográficos
Autores principales:	Panevska, Anastasija, Čegovnik, Nastja, Fortuna, Klavdija, Vukovič, Alen, Grundner, Maja, Modic, Špela, Bajc, Gregor, Skočaj, Matej, Mravinec Bohte, Martina, Popošek, Lara Larisa, Žigon, Primož, Razinger, Jaka, Veranič, Peter, Resnik, Nataša, Sepčić, Kristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905591/ https://www.ncbi.nlm.nih.gov/pubmed/36750638 http://dx.doi.org/10.1038/s41598-023-28949-7

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