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UCHL1 regulated by Sp1 ameliorates cochlear hair cell senescence and oxidative damage

Age-related hearing loss (ARHL) is the most common cause of hearing loss in the elderly. Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme involved in several types of human disease. The present study aimed to investigate the effect of UCHL1 on a hydrogen peroxide (H(2)O(...

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Detalles Bibliográficos
Autores principales:	Li, Lihua, Xu, Kai, Bai, Xue, Wang, Zhi, Tian, Xiaoyan, Chen, Xubo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905655/ https://www.ncbi.nlm.nih.gov/pubmed/36761006 http://dx.doi.org/10.3892/etm.2023.11793

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