Cargando…

Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male

Adrenocortical oncocytic carcinoma is a rare type of adrenocortical tumor. Its clinical characteristics and biological behavior need to be further evaluated after the accumulation of cases. Here we report a case of adrenocortical oncocytic carcinoma in an Asian male with scoliosis. We performed an o...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Hongtao, Huang, Kai, Liu, Dan, Wang, Yehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905669/
https://www.ncbi.nlm.nih.gov/pubmed/36761025
http://dx.doi.org/10.3389/fsurg.2023.943296
_version_ 1784883847603683328
author Liu, Hongtao
Huang, Kai
Liu, Dan
Wang, Yehua
author_facet Liu, Hongtao
Huang, Kai
Liu, Dan
Wang, Yehua
author_sort Liu, Hongtao
collection PubMed
description Adrenocortical oncocytic carcinoma is a rare type of adrenocortical tumor. Its clinical characteristics and biological behavior need to be further evaluated after the accumulation of cases. Here we report a case of adrenocortical oncocytic carcinoma in an Asian male with scoliosis. We performed an operation on this patient. Because the patient's scoliosis was limited during the operation and the tumor protruded into the chest, we decided to adopt open surgery in the supine position. During the operation, we found a tumor about 8 cm in diameter in the right adrenal region and successfully removed it. The patient recovered well after surgery, and there was no tumor recurrence after one year of follow-up. Pathological results confirmed the diagnosis of adrenocortical oncocytic carcinoma. Pathological features showed tumor cell invasion of adipose tissue, with atypical mitosis and abundant esinophilic cytoplasm. Immunohistochemistry showed that nucleus related antigen (Ki67) index was more than 15% and the positive pathological staining of Synaptophysin (Syn), Melanoma A (Melan A), Inhibin and calretinin. The incidence rate of adrenocortical oncocytic carcinoma is extremely rare. Abdominal Computed tomography (CT) scans and other imaging examination methods are not specific. For larger adrenal tumors, the diagnosis of this disease should be considered. For patients with adrenocortical oncocytic carcinoma who have not yet metastasized, we may achieve sound treatment effects and reduce recurrence by removing the tumor, retroperitoneal fat around the tumor and locoregional lymph nodes.
format Online
Article
Text
id pubmed-9905669
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-99056692023-02-08 Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male Liu, Hongtao Huang, Kai Liu, Dan Wang, Yehua Front Surg Surgery Adrenocortical oncocytic carcinoma is a rare type of adrenocortical tumor. Its clinical characteristics and biological behavior need to be further evaluated after the accumulation of cases. Here we report a case of adrenocortical oncocytic carcinoma in an Asian male with scoliosis. We performed an operation on this patient. Because the patient's scoliosis was limited during the operation and the tumor protruded into the chest, we decided to adopt open surgery in the supine position. During the operation, we found a tumor about 8 cm in diameter in the right adrenal region and successfully removed it. The patient recovered well after surgery, and there was no tumor recurrence after one year of follow-up. Pathological results confirmed the diagnosis of adrenocortical oncocytic carcinoma. Pathological features showed tumor cell invasion of adipose tissue, with atypical mitosis and abundant esinophilic cytoplasm. Immunohistochemistry showed that nucleus related antigen (Ki67) index was more than 15% and the positive pathological staining of Synaptophysin (Syn), Melanoma A (Melan A), Inhibin and calretinin. The incidence rate of adrenocortical oncocytic carcinoma is extremely rare. Abdominal Computed tomography (CT) scans and other imaging examination methods are not specific. For larger adrenal tumors, the diagnosis of this disease should be considered. For patients with adrenocortical oncocytic carcinoma who have not yet metastasized, we may achieve sound treatment effects and reduce recurrence by removing the tumor, retroperitoneal fat around the tumor and locoregional lymph nodes. Frontiers Media S.A. 2023-01-25 /pmc/articles/PMC9905669/ /pubmed/36761025 http://dx.doi.org/10.3389/fsurg.2023.943296 Text en © 2023 Liu, Huang, Liu and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Liu, Hongtao
Huang, Kai
Liu, Dan
Wang, Yehua
Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male
title Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male
title_full Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male
title_fullStr Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male
title_full_unstemmed Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male
title_short Case Report: Surgery to remove adrenocortical oncocytic carcinoma from an Asian male
title_sort case report: surgery to remove adrenocortical oncocytic carcinoma from an asian male
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905669/
https://www.ncbi.nlm.nih.gov/pubmed/36761025
http://dx.doi.org/10.3389/fsurg.2023.943296
work_keys_str_mv AT liuhongtao casereportsurgerytoremoveadrenocorticaloncocyticcarcinomafromanasianmale
AT huangkai casereportsurgerytoremoveadrenocorticaloncocyticcarcinomafromanasianmale
AT liudan casereportsurgerytoremoveadrenocorticaloncocyticcarcinomafromanasianmale
AT wangyehua casereportsurgerytoremoveadrenocorticaloncocyticcarcinomafromanasianmale