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Negative interference with antibody-dependent cellular cytotoxicity mediated by rituximab from its interactions with human serum proteins
Although interactions of small molecular drugs with serum proteins have been widely studied from pharmacokinetic and pharmacodynamic perspectives, there have been few reports on the effects of serum components on therapeutic antibody functions. This study reports the effect of abundant serum protein...
Autores principales: | Yanaka, Saeko, Yogo, Rina, Yagi, Hirokazu, Onitsuka, Masayoshi, Wakaizumi, Natsumi, Yamaguchi, Yuki, Uchiyama, Susumu, Kato, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905677/ https://www.ncbi.nlm.nih.gov/pubmed/36761774 http://dx.doi.org/10.3389/fimmu.2023.1090898 |
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