Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols

Metabolites are closely intertwined genotypes that can provide clear information about the final phenotype. The high-throughput analysis platform used to identify candidate metabolites and describe their contributions can help to quickly detect metabolic characteristics from large spectral data, whi...

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Autores principales: Qiu, Shi, Guo, Sifan, Yang, Qiang, Xie, Yiqiang, Tang, Songqi, Zhang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905695/
https://www.ncbi.nlm.nih.gov/pubmed/36762198
http://dx.doi.org/10.3389/fchem.2023.1129717
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author Qiu, Shi
Guo, Sifan
Yang, Qiang
Xie, Yiqiang
Tang, Songqi
Zhang, Aihua
author_facet Qiu, Shi
Guo, Sifan
Yang, Qiang
Xie, Yiqiang
Tang, Songqi
Zhang, Aihua
author_sort Qiu, Shi
collection PubMed
description Metabolites are closely intertwined genotypes that can provide clear information about the final phenotype. The high-throughput analysis platform used to identify candidate metabolites and describe their contributions can help to quickly detect metabolic characteristics from large spectral data, which may lead to peak data preprocessing, statistical analysis and functional interpretation. Developing a comprehensive strategy for discovering and verifying bioactive metabolites can provide a large number of new functional biomarkers, and then more closely reveal their functional changes, which has relevant biological significance for disease diagnosis and prognosis treatment.
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spelling pubmed-99056952023-02-08 Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols Qiu, Shi Guo, Sifan Yang, Qiang Xie, Yiqiang Tang, Songqi Zhang, Aihua Front Chem Chemistry Metabolites are closely intertwined genotypes that can provide clear information about the final phenotype. The high-throughput analysis platform used to identify candidate metabolites and describe their contributions can help to quickly detect metabolic characteristics from large spectral data, which may lead to peak data preprocessing, statistical analysis and functional interpretation. Developing a comprehensive strategy for discovering and verifying bioactive metabolites can provide a large number of new functional biomarkers, and then more closely reveal their functional changes, which has relevant biological significance for disease diagnosis and prognosis treatment. Frontiers Media S.A. 2023-01-25 /pmc/articles/PMC9905695/ /pubmed/36762198 http://dx.doi.org/10.3389/fchem.2023.1129717 Text en Copyright © 2023 Qiu, Guo, Yang, Xie, Tang and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Qiu, Shi
Guo, Sifan
Yang, Qiang
Xie, Yiqiang
Tang, Songqi
Zhang, Aihua
Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols
title Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols
title_full Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols
title_fullStr Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols
title_full_unstemmed Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols
title_short Innovation in identifying metabolites from complex metabolome—Highlights of recent analytical platforms and protocols
title_sort innovation in identifying metabolites from complex metabolome—highlights of recent analytical platforms and protocols
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905695/
https://www.ncbi.nlm.nih.gov/pubmed/36762198
http://dx.doi.org/10.3389/fchem.2023.1129717
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