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The helminth derived peptide FhHDM-1 redirects macrophage metabolism towards glutaminolysis to regulate the pro-inflammatory response
We have previously identified an immune modulating peptide, termed FhHDM-1, within the secretions of the liver fluke, Fasciola hepatica, which is sufficiently potent to prevent the progression of type 1 diabetes and multiple sclerosis in murine models of disease. Here, we have determined that the Fh...
Autores principales: | Quinteros, Susel Loli, von Krusenstiern, Eliana, Snyder, Nathaniel W., Tanaka, Akane, O’Brien, Bronwyn, Donnelly, Sheila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905698/ https://www.ncbi.nlm.nih.gov/pubmed/36761766 http://dx.doi.org/10.3389/fimmu.2023.1018076 |
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