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The helminth derived peptide FhHDM-1 redirects macrophage metabolism towards glutaminolysis to regulate the pro-inflammatory response

We have previously identified an immune modulating peptide, termed FhHDM-1, within the secretions of the liver fluke, Fasciola hepatica, which is sufficiently potent to prevent the progression of type 1 diabetes and multiple sclerosis in murine models of disease. Here, we have determined that the Fh...

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Detalles Bibliográficos
Autores principales: Quinteros, Susel Loli, von Krusenstiern, Eliana, Snyder, Nathaniel W., Tanaka, Akane, O’Brien, Bronwyn, Donnelly, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905698/
https://www.ncbi.nlm.nih.gov/pubmed/36761766
http://dx.doi.org/10.3389/fimmu.2023.1018076

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