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Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma
Low-grade malignant eccrine spiradenoma (spiradenocarcinoma) is a rare sweat gland tumor, which usually arises from a pre-existing benign eccrine spiradenoma. This paper presents the case of a 55-year-old male who had a lesion in his right elbow for 10 years. The microscopic examination revealed a w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Dermatological Association; The Korean Society for Investigative Dermatology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905852/ https://www.ncbi.nlm.nih.gov/pubmed/36750462 http://dx.doi.org/10.5021/ad.20.226 |
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author | Akgun, Gizem Akkas Ahmedov, Anvar Parlar, Ali İhsan Metineren, Mehmet Hüseyin Deger, Ayse Nur |
author_facet | Akgun, Gizem Akkas Ahmedov, Anvar Parlar, Ali İhsan Metineren, Mehmet Hüseyin Deger, Ayse Nur |
author_sort | Akgun, Gizem Akkas |
collection | PubMed |
description | Low-grade malignant eccrine spiradenoma (spiradenocarcinoma) is a rare sweat gland tumor, which usually arises from a pre-existing benign eccrine spiradenoma. This paper presents the case of a 55-year-old male who had a lesion in his right elbow for 10 years. The microscopic examination revealed a well-demarcated, multilobulated tumor in the dermis and subcutis, which presented with many blood-filled vessels and extensive hemorrhage. The tumor was composed of hyperchromatic, round to oval cells with nucleolar prominence, mild to moderate atypia, and increased mitotic index. Additionally, lymphangiectatic appearance was observed in areas with prominent stromal lymphedema. P53 and Ki-67 had high positivity. Surgical excision of the lesion was performed with adequate surgical margins, and the dissected lymph nodes in the axilla were tumor-negative. After 15 months of follow-up, there was no recurrence or distant metastasis. |
format | Online Article Text |
id | pubmed-9905852 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Korean Dermatological Association; The Korean Society for Investigative Dermatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-99058522023-02-16 Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma Akgun, Gizem Akkas Ahmedov, Anvar Parlar, Ali İhsan Metineren, Mehmet Hüseyin Deger, Ayse Nur Ann Dermatol Case Report Low-grade malignant eccrine spiradenoma (spiradenocarcinoma) is a rare sweat gland tumor, which usually arises from a pre-existing benign eccrine spiradenoma. This paper presents the case of a 55-year-old male who had a lesion in his right elbow for 10 years. The microscopic examination revealed a well-demarcated, multilobulated tumor in the dermis and subcutis, which presented with many blood-filled vessels and extensive hemorrhage. The tumor was composed of hyperchromatic, round to oval cells with nucleolar prominence, mild to moderate atypia, and increased mitotic index. Additionally, lymphangiectatic appearance was observed in areas with prominent stromal lymphedema. P53 and Ki-67 had high positivity. Surgical excision of the lesion was performed with adequate surgical margins, and the dissected lymph nodes in the axilla were tumor-negative. After 15 months of follow-up, there was no recurrence or distant metastasis. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2023-02 2023-01-20 /pmc/articles/PMC9905852/ /pubmed/36750462 http://dx.doi.org/10.5021/ad.20.226 Text en Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Akgun, Gizem Akkas Ahmedov, Anvar Parlar, Ali İhsan Metineren, Mehmet Hüseyin Deger, Ayse Nur Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma |
title | Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma |
title_full | Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma |
title_fullStr | Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma |
title_full_unstemmed | Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma |
title_short | Lymphangiectatic Variant of Low-Grade Malignant Eccrine Spiradenoma |
title_sort | lymphangiectatic variant of low-grade malignant eccrine spiradenoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905852/ https://www.ncbi.nlm.nih.gov/pubmed/36750462 http://dx.doi.org/10.5021/ad.20.226 |
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