Reinstating apoptosis using putative Bcl-xL natural product inhibitors: Molecular docking and ADMETox profiling investigations

OBJECTIVES: While a fine balance in the pro-apoptotic and anti-apoptotic family members of the B-cell lymphoma-2 (Bcl-2) protein family represents a normal signaling profile, a tilt in balance towards anti-apoptotic family members has fortified different forms of cancers with survival advantage and...

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Detalles Bibliográficos
Autores principales: Boyenle, Ibrahim Damilare, Ogunlana, Abdeen Tunde, Kehinde Oyedele, Abdul-Quddus, Olokodana, Babatunde Kazeem, Owolabi, Nurudeen, Salahudeen, Abdulmalik, Aderenle, Oluwafemi Timothy, Oloyede, Taiwo Oluwafisayomi, Adelusi, Temitope Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906007/
https://www.ncbi.nlm.nih.gov/pubmed/36818176
http://dx.doi.org/10.1016/j.jtumed.2022.10.014

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