Cargando…

Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children

While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were av...

Descripción completa

Detalles Bibliográficos
Autores principales: Hall, Nigel J, Sherratt, Frances C, Eaton, Simon, Walker, Erin, Chorozoglou, Maria, Beasant, Lucy, Stanton, Michael, Corbett, Harriet, Rex, Dean, Hutchings, Natalie, Dixon, Elizabeth, Crawley, Esther, Blazeby, Jane, Young, Bridget, Reading, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906255/
https://www.ncbi.nlm.nih.gov/pubmed/36746524
http://dx.doi.org/10.1136/bmjpo-2022-001673
_version_ 1784883961653100544
author Hall, Nigel J
Sherratt, Frances C
Eaton, Simon
Walker, Erin
Chorozoglou, Maria
Beasant, Lucy
Stanton, Michael
Corbett, Harriet
Rex, Dean
Hutchings, Natalie
Dixon, Elizabeth
Crawley, Esther
Blazeby, Jane
Young, Bridget
Reading, Isabel
author_facet Hall, Nigel J
Sherratt, Frances C
Eaton, Simon
Walker, Erin
Chorozoglou, Maria
Beasant, Lucy
Stanton, Michael
Corbett, Harriet
Rex, Dean
Hutchings, Natalie
Dixon, Elizabeth
Crawley, Esther
Blazeby, Jane
Young, Bridget
Reading, Isabel
author_sort Hall, Nigel J
collection PubMed
description While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT. Trial registration number is ISRCTN15830435.
format Online
Article
Text
id pubmed-9906255
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-99062552023-02-08 Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children Hall, Nigel J Sherratt, Frances C Eaton, Simon Walker, Erin Chorozoglou, Maria Beasant, Lucy Stanton, Michael Corbett, Harriet Rex, Dean Hutchings, Natalie Dixon, Elizabeth Crawley, Esther Blazeby, Jane Young, Bridget Reading, Isabel BMJ Paediatr Open Original Research Letter While non-operative treatment has emerged as an alternative to surgery for the treatment of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these in a feasibility randomised trial. Of 57 randomised participants, data were available for 26. Compared with appendicectomy, children allocated to non-operative treatment reported higher short-term quality of life scores, shorter duration of requiring analgesia, more rapid return to normal activities and shorter parental absence from work. These preliminary data suggest differences exist in recovery profile and quality of life between these treatments that are important to measure in a larger RCT. Trial registration number is ISRCTN15830435. BMJ Publishing Group 2023-02-06 /pmc/articles/PMC9906255/ /pubmed/36746524 http://dx.doi.org/10.1136/bmjpo-2022-001673 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Research Letter
Hall, Nigel J
Sherratt, Frances C
Eaton, Simon
Walker, Erin
Chorozoglou, Maria
Beasant, Lucy
Stanton, Michael
Corbett, Harriet
Rex, Dean
Hutchings, Natalie
Dixon, Elizabeth
Crawley, Esther
Blazeby, Jane
Young, Bridget
Reading, Isabel
Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
title Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
title_full Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
title_fullStr Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
title_full_unstemmed Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
title_short Patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
title_sort patient-centred outcomes following non-operative treatment or appendicectomy for uncomplicated acute appendicitis in children
topic Original Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906255/
https://www.ncbi.nlm.nih.gov/pubmed/36746524
http://dx.doi.org/10.1136/bmjpo-2022-001673
work_keys_str_mv AT hallnigelj patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT sherrattfrancesc patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT eatonsimon patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT walkererin patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT chorozogloumaria patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT beasantlucy patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT stantonmichael patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT corbettharriet patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT rexdean patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT hutchingsnatalie patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT dixonelizabeth patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT crawleyesther patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT blazebyjane patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT youngbridget patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren
AT readingisabel patientcentredoutcomesfollowingnonoperativetreatmentorappendicectomyforuncomplicatedacuteappendicitisinchildren