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Effects of nebulized antithrombin and heparin on inflammatory and coagulation alterations in an acute lung injury model in rats

BACKGROUND: During acute respiratory distress syndrome, proinflammatory mediators inhibit natural anticoagulant factors, which alter the normal balance between coagulation and fibrinolysis leading to a procoagulant state. We hypothesize that pulmonary administration of anticoagulants might be benefi...

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Detalles Bibliográficos
Autores principales: Camprubí‐Rimblas, Marta, Tantinyà, Neus, Guillamat‐Prats, Raquel, Bringué, Josep, Puig, Ferranda, Gómez, Maria Nieves, Blanch, Lluís, Artigas, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906372/
https://www.ncbi.nlm.nih.gov/pubmed/31755229
http://dx.doi.org/10.1111/jth.14685