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Effects of nebulized antithrombin and heparin on inflammatory and coagulation alterations in an acute lung injury model in rats
BACKGROUND: During acute respiratory distress syndrome, proinflammatory mediators inhibit natural anticoagulant factors, which alter the normal balance between coagulation and fibrinolysis leading to a procoagulant state. We hypothesize that pulmonary administration of anticoagulants might be benefi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Society on Thrombosis and Haemostasis. Published by Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906372/ https://www.ncbi.nlm.nih.gov/pubmed/31755229 http://dx.doi.org/10.1111/jth.14685 |