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Targeting Cbl-b in cancer immunotherapy

Cancer immunotherapy with immune-checkpoint blockade has improved the outcomes of patients with various malignancies, yet a majority do not benefit or develop resistance. To address this unmet need, efforts across the field are targeting additional coinhibitory receptors, costimulatory proteins, and...

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Detalles Bibliográficos
Autores principales: Augustin, Ryan C., Bao, Riyue, Luke, Jason J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906388/
https://www.ncbi.nlm.nih.gov/pubmed/36750253
http://dx.doi.org/10.1136/jitc-2022-006007