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Protein Kinase A (PKA) as a Master Regulator of the Early Metabolic Reprogramming in Bone Metastatic Prostate Cancer Cells

The arrival of metastatic prostate cancer (PCa) tumor cells to the bone niche requires a metabolic adaptation. We sought to identify metabolic dysregulations fueling PCa metastasis, modulated by bone secreted factors. METHODS: By an indirect co-culture system of PCa (PC3) and bone progenitors (MC3T3...

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Detalles Bibliográficos
Autores principales: Sanchis, Pablo, Anselmino, Nicolas, Lavignolle, Rosario, Sabater, Agustina, Labanca, Estefania, Bizzotto, Juan, Lage-Vickers, Sofia, Pascual, Gaston, Seniuk, Rocio, Toro, Ayelen, Navone, Nora, Cotignola, Javier, Vazquez, Elba, Gueron, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906520/
http://dx.doi.org/10.1200/GO.22.35000

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