Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice

Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid that regulates fundamental cellular processes such as proliferation, migration, apoptosis, and differentiation through 5 cognate G protein–coupled receptors (S1P(1)-S1P(5)). We previously demonstrated that blockade of S1P(2) signaling in S1P(...

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Detalles Bibliográficos
Autores principales: Asano, Motochika, Kajita, Kazuo, Fuwa, Masayuki, Kajita, Toshiko, Mori, Ichiro, Akahoshi, Noriyuki, Ishii, Isao, Morita, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906621/
https://www.ncbi.nlm.nih.gov/pubmed/36690339
http://dx.doi.org/10.1210/endocr/bqad019

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