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Amorphous Drug–Polymer Salts: Maximizing Proton Transfer to Enhance Stability and Release
[Image: see text] An amorphous drug–polymer salt (ADPS) can be remarkably stable against crystallization at high temperature and humidity (e.g., 40°C/75% RH) and provide fast release. Here, we report that process conditions strongly influence the degree of proton transfer (salt formation) between a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906740/ https://www.ncbi.nlm.nih.gov/pubmed/36668815 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00942 |