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Rhabdomyolysis Related to Red Yeast Rice Ingestion

Red yeast rice is made by fermenting white rice with the fungus Monascus purpureus. It has lipid-lowering effects due to the presence of monacolin, produced by the fungus, and therefore shares the same biological and side effects as a statin, namely it may cause rhabdomyolysis. In this clinical case...

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Autores principales: Santos, Sara, Gomes, Sara, Carvalho, Inês, Bonito, Inês, Carmo, Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906798/
https://www.ncbi.nlm.nih.gov/pubmed/36779111
http://dx.doi.org/10.7759/cureus.33532
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author Santos, Sara
Gomes, Sara
Carvalho, Inês
Bonito, Inês
Carmo, Célia
author_facet Santos, Sara
Gomes, Sara
Carvalho, Inês
Bonito, Inês
Carmo, Célia
author_sort Santos, Sara
collection PubMed
description Red yeast rice is made by fermenting white rice with the fungus Monascus purpureus. It has lipid-lowering effects due to the presence of monacolin, produced by the fungus, and therefore shares the same biological and side effects as a statin, namely it may cause rhabdomyolysis. In this clinical case study, we report the case of a 50-year-old woman suffering from a sudden onset of chest discomfort and generalized myalgia. Laboratory findings were consistent with the diagnosis of rhabdomyolysis. The patient had been recently diagnosed with dyslipidemia in primary care, and decided to start eating red yeast rice, without informing clinicians. Clinical improvement was rapidly noticed after hydration, and blood sample results returned to normal. Awareness should be raised for the regulation of these products, as their consumption is rising, and patients are unaware of their potential side effects. 
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spelling pubmed-99067982023-02-09 Rhabdomyolysis Related to Red Yeast Rice Ingestion Santos, Sara Gomes, Sara Carvalho, Inês Bonito, Inês Carmo, Célia Cureus Endocrinology/Diabetes/Metabolism Red yeast rice is made by fermenting white rice with the fungus Monascus purpureus. It has lipid-lowering effects due to the presence of monacolin, produced by the fungus, and therefore shares the same biological and side effects as a statin, namely it may cause rhabdomyolysis. In this clinical case study, we report the case of a 50-year-old woman suffering from a sudden onset of chest discomfort and generalized myalgia. Laboratory findings were consistent with the diagnosis of rhabdomyolysis. The patient had been recently diagnosed with dyslipidemia in primary care, and decided to start eating red yeast rice, without informing clinicians. Clinical improvement was rapidly noticed after hydration, and blood sample results returned to normal. Awareness should be raised for the regulation of these products, as their consumption is rising, and patients are unaware of their potential side effects.  Cureus 2023-01-09 /pmc/articles/PMC9906798/ /pubmed/36779111 http://dx.doi.org/10.7759/cureus.33532 Text en Copyright © 2023, Santos et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Santos, Sara
Gomes, Sara
Carvalho, Inês
Bonito, Inês
Carmo, Célia
Rhabdomyolysis Related to Red Yeast Rice Ingestion
title Rhabdomyolysis Related to Red Yeast Rice Ingestion
title_full Rhabdomyolysis Related to Red Yeast Rice Ingestion
title_fullStr Rhabdomyolysis Related to Red Yeast Rice Ingestion
title_full_unstemmed Rhabdomyolysis Related to Red Yeast Rice Ingestion
title_short Rhabdomyolysis Related to Red Yeast Rice Ingestion
title_sort rhabdomyolysis related to red yeast rice ingestion
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906798/
https://www.ncbi.nlm.nih.gov/pubmed/36779111
http://dx.doi.org/10.7759/cureus.33532
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