Stoking inflammasome fires in the COVID-19 neighborhood

The cellular and molecular sources of elevated IL-1β and IL-6 in COVID-19 remain unclear. In this issue of Cell Host and Microbe, Barnett et al. determine how immune cells sense SARS-CoV-2 infection in neighboring epithelial cells to trigger inflammasome signaling and IL-1β release, which in turn pr...

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Detalles Bibliográficos
Autores principales: Labzin, Larisa I., Schroder, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906827/
https://www.ncbi.nlm.nih.gov/pubmed/36758516
http://dx.doi.org/10.1016/j.chom.2023.01.008
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author Labzin, Larisa I.
Schroder, Kate
author_facet Labzin, Larisa I.
Schroder, Kate
author_sort Labzin, Larisa I.
collection PubMed
description The cellular and molecular sources of elevated IL-1β and IL-6 in COVID-19 remain unclear. In this issue of Cell Host and Microbe, Barnett et al. determine how immune cells sense SARS-CoV-2 infection in neighboring epithelial cells to trigger inflammasome signaling and IL-1β release, which in turn promotes IL-6 release.
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spelling pubmed-99068272023-02-08 Stoking inflammasome fires in the COVID-19 neighborhood Labzin, Larisa I. Schroder, Kate Cell Host Microbe Preview The cellular and molecular sources of elevated IL-1β and IL-6 in COVID-19 remain unclear. In this issue of Cell Host and Microbe, Barnett et al. determine how immune cells sense SARS-CoV-2 infection in neighboring epithelial cells to trigger inflammasome signaling and IL-1β release, which in turn promotes IL-6 release. Elsevier Inc. 2023-02-08 2023-02-08 /pmc/articles/PMC9906827/ /pubmed/36758516 http://dx.doi.org/10.1016/j.chom.2023.01.008 Text en © 2023 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Preview
Labzin, Larisa I.
Schroder, Kate
Stoking inflammasome fires in the COVID-19 neighborhood
title Stoking inflammasome fires in the COVID-19 neighborhood
title_full Stoking inflammasome fires in the COVID-19 neighborhood
title_fullStr Stoking inflammasome fires in the COVID-19 neighborhood
title_full_unstemmed Stoking inflammasome fires in the COVID-19 neighborhood
title_short Stoking inflammasome fires in the COVID-19 neighborhood
title_sort stoking inflammasome fires in the covid-19 neighborhood
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906827/
https://www.ncbi.nlm.nih.gov/pubmed/36758516
http://dx.doi.org/10.1016/j.chom.2023.01.008
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