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Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation

BACKGROUND: Chronic kidney disease (CKD) patients sustain a fairly high prevalence of cardiovascular disease (CVD). Microvascular inflammation is an early manifestation of CVD, and the released mitochondrial DNA (MtDNA) has been proposed to be a crucial integrator of inflammatory signals. Herein, th...

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Detalles Bibliográficos
Autores principales: Fan, Zhen, Feng, Ya, Zang, Li, Guo, Yi, Zhong, Xiao-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906832/
https://www.ncbi.nlm.nih.gov/pubmed/36755219
http://dx.doi.org/10.1186/s12872-023-03104-2