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Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV

BACKGROUND: Antiretroviral therapy (ART) is currently the most effective way to treat people living with human immunodeficiency virus (PLHs) and reduce HIV transmission. While there are many factors that reduce adherence to ART, PLHs’ knowledge about ART may determine the level of adherence. It is n...

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Autores principales: Xu, Di, Shi, Yuhua, Pan, Ling, Duan, Qiongli, Huang, Nengmei, Liu, Pengcheng, Han, Jing, Liu, Zhongfu, Li, Jian, Liu, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906841/
https://www.ncbi.nlm.nih.gov/pubmed/36750811
http://dx.doi.org/10.1186/s12889-023-15220-x
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author Xu, Di
Shi, Yuhua
Pan, Ling
Duan, Qiongli
Huang, Nengmei
Liu, Pengcheng
Han, Jing
Liu, Zhongfu
Li, Jian
Liu, Hongjie
author_facet Xu, Di
Shi, Yuhua
Pan, Ling
Duan, Qiongli
Huang, Nengmei
Liu, Pengcheng
Han, Jing
Liu, Zhongfu
Li, Jian
Liu, Hongjie
author_sort Xu, Di
collection PubMed
description BACKGROUND: Antiretroviral therapy (ART) is currently the most effective way to treat people living with human immunodeficiency virus (PLHs) and reduce HIV transmission. While there are many factors that reduce adherence to ART, PLHs’ knowledge about ART may determine the level of adherence. It is necessary to design and assess an instrument scale that measures the knowledge of antiretroviral therapy among PLHs. METHOD: A cross-sectional study was conducted among PLHs in Honghe Hani and Yi Autonomous Prefecture, China. Both exploratory and confirmatory factor analyses were used to examine the latent factors of antiretroviral therapy knowledge scale. Internal consistency was assessed separately for the scale and its dimensions by estimating Cronbach’s alphas, split-half reliability and Spearman’s correlation coefficient. ANOVAs were used to compare the scores of different dimensions with sociodemographic characteristics. RESULTS: Four factors were extracted according to factor loadings. They had high internal consistency reliability (Cronbach’s alpha: 0.70–0.95) and good construct validity (standardized factor loading range: 0.46–0.86) in the scale. Goodness of fit indices indicated that a four-factor solution fit the data at an accepted level (χ(2)/degree ratio = 1.980, RMSEA = 0.069, GFI = 0.909, CFI = 0.957, NFI = 0.917, TLI = 0.944). ANOVAs indicated that the score was higher among PLHs who were Han, had spouses/partners, were non-famers or migrant workers, initiated ART, and had a high school or above education. CONCLUSION: The psychometric assessment indicated that this ART knowledge scale had accepted internal consistency and discriminant construct validity. It can be used to assess the knowledge of antiretroviral therapy for PLHs.
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spelling pubmed-99068412023-02-08 Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV Xu, Di Shi, Yuhua Pan, Ling Duan, Qiongli Huang, Nengmei Liu, Pengcheng Han, Jing Liu, Zhongfu Li, Jian Liu, Hongjie BMC Public Health Research BACKGROUND: Antiretroviral therapy (ART) is currently the most effective way to treat people living with human immunodeficiency virus (PLHs) and reduce HIV transmission. While there are many factors that reduce adherence to ART, PLHs’ knowledge about ART may determine the level of adherence. It is necessary to design and assess an instrument scale that measures the knowledge of antiretroviral therapy among PLHs. METHOD: A cross-sectional study was conducted among PLHs in Honghe Hani and Yi Autonomous Prefecture, China. Both exploratory and confirmatory factor analyses were used to examine the latent factors of antiretroviral therapy knowledge scale. Internal consistency was assessed separately for the scale and its dimensions by estimating Cronbach’s alphas, split-half reliability and Spearman’s correlation coefficient. ANOVAs were used to compare the scores of different dimensions with sociodemographic characteristics. RESULTS: Four factors were extracted according to factor loadings. They had high internal consistency reliability (Cronbach’s alpha: 0.70–0.95) and good construct validity (standardized factor loading range: 0.46–0.86) in the scale. Goodness of fit indices indicated that a four-factor solution fit the data at an accepted level (χ(2)/degree ratio = 1.980, RMSEA = 0.069, GFI = 0.909, CFI = 0.957, NFI = 0.917, TLI = 0.944). ANOVAs indicated that the score was higher among PLHs who were Han, had spouses/partners, were non-famers or migrant workers, initiated ART, and had a high school or above education. CONCLUSION: The psychometric assessment indicated that this ART knowledge scale had accepted internal consistency and discriminant construct validity. It can be used to assess the knowledge of antiretroviral therapy for PLHs. BioMed Central 2023-02-07 /pmc/articles/PMC9906841/ /pubmed/36750811 http://dx.doi.org/10.1186/s12889-023-15220-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Xu, Di
Shi, Yuhua
Pan, Ling
Duan, Qiongli
Huang, Nengmei
Liu, Pengcheng
Han, Jing
Liu, Zhongfu
Li, Jian
Liu, Hongjie
Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
title Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
title_full Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
title_fullStr Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
title_full_unstemmed Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
title_short Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
title_sort assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with hiv
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906841/
https://www.ncbi.nlm.nih.gov/pubmed/36750811
http://dx.doi.org/10.1186/s12889-023-15220-x
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