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Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV
BACKGROUND: Antiretroviral therapy (ART) is currently the most effective way to treat people living with human immunodeficiency virus (PLHs) and reduce HIV transmission. While there are many factors that reduce adherence to ART, PLHs’ knowledge about ART may determine the level of adherence. It is n...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906841/ https://www.ncbi.nlm.nih.gov/pubmed/36750811 http://dx.doi.org/10.1186/s12889-023-15220-x |
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author | Xu, Di Shi, Yuhua Pan, Ling Duan, Qiongli Huang, Nengmei Liu, Pengcheng Han, Jing Liu, Zhongfu Li, Jian Liu, Hongjie |
author_facet | Xu, Di Shi, Yuhua Pan, Ling Duan, Qiongli Huang, Nengmei Liu, Pengcheng Han, Jing Liu, Zhongfu Li, Jian Liu, Hongjie |
author_sort | Xu, Di |
collection | PubMed |
description | BACKGROUND: Antiretroviral therapy (ART) is currently the most effective way to treat people living with human immunodeficiency virus (PLHs) and reduce HIV transmission. While there are many factors that reduce adherence to ART, PLHs’ knowledge about ART may determine the level of adherence. It is necessary to design and assess an instrument scale that measures the knowledge of antiretroviral therapy among PLHs. METHOD: A cross-sectional study was conducted among PLHs in Honghe Hani and Yi Autonomous Prefecture, China. Both exploratory and confirmatory factor analyses were used to examine the latent factors of antiretroviral therapy knowledge scale. Internal consistency was assessed separately for the scale and its dimensions by estimating Cronbach’s alphas, split-half reliability and Spearman’s correlation coefficient. ANOVAs were used to compare the scores of different dimensions with sociodemographic characteristics. RESULTS: Four factors were extracted according to factor loadings. They had high internal consistency reliability (Cronbach’s alpha: 0.70–0.95) and good construct validity (standardized factor loading range: 0.46–0.86) in the scale. Goodness of fit indices indicated that a four-factor solution fit the data at an accepted level (χ(2)/degree ratio = 1.980, RMSEA = 0.069, GFI = 0.909, CFI = 0.957, NFI = 0.917, TLI = 0.944). ANOVAs indicated that the score was higher among PLHs who were Han, had spouses/partners, were non-famers or migrant workers, initiated ART, and had a high school or above education. CONCLUSION: The psychometric assessment indicated that this ART knowledge scale had accepted internal consistency and discriminant construct validity. It can be used to assess the knowledge of antiretroviral therapy for PLHs. |
format | Online Article Text |
id | pubmed-9906841 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-99068412023-02-08 Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV Xu, Di Shi, Yuhua Pan, Ling Duan, Qiongli Huang, Nengmei Liu, Pengcheng Han, Jing Liu, Zhongfu Li, Jian Liu, Hongjie BMC Public Health Research BACKGROUND: Antiretroviral therapy (ART) is currently the most effective way to treat people living with human immunodeficiency virus (PLHs) and reduce HIV transmission. While there are many factors that reduce adherence to ART, PLHs’ knowledge about ART may determine the level of adherence. It is necessary to design and assess an instrument scale that measures the knowledge of antiretroviral therapy among PLHs. METHOD: A cross-sectional study was conducted among PLHs in Honghe Hani and Yi Autonomous Prefecture, China. Both exploratory and confirmatory factor analyses were used to examine the latent factors of antiretroviral therapy knowledge scale. Internal consistency was assessed separately for the scale and its dimensions by estimating Cronbach’s alphas, split-half reliability and Spearman’s correlation coefficient. ANOVAs were used to compare the scores of different dimensions with sociodemographic characteristics. RESULTS: Four factors were extracted according to factor loadings. They had high internal consistency reliability (Cronbach’s alpha: 0.70–0.95) and good construct validity (standardized factor loading range: 0.46–0.86) in the scale. Goodness of fit indices indicated that a four-factor solution fit the data at an accepted level (χ(2)/degree ratio = 1.980, RMSEA = 0.069, GFI = 0.909, CFI = 0.957, NFI = 0.917, TLI = 0.944). ANOVAs indicated that the score was higher among PLHs who were Han, had spouses/partners, were non-famers or migrant workers, initiated ART, and had a high school or above education. CONCLUSION: The psychometric assessment indicated that this ART knowledge scale had accepted internal consistency and discriminant construct validity. It can be used to assess the knowledge of antiretroviral therapy for PLHs. BioMed Central 2023-02-07 /pmc/articles/PMC9906841/ /pubmed/36750811 http://dx.doi.org/10.1186/s12889-023-15220-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Xu, Di Shi, Yuhua Pan, Ling Duan, Qiongli Huang, Nengmei Liu, Pengcheng Han, Jing Liu, Zhongfu Li, Jian Liu, Hongjie Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV |
title | Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV |
title_full | Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV |
title_fullStr | Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV |
title_full_unstemmed | Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV |
title_short | Assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with HIV |
title_sort | assessment of an instrument scale measuring the knowledge of antiretroviral therapy among people living with hiv |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906841/ https://www.ncbi.nlm.nih.gov/pubmed/36750811 http://dx.doi.org/10.1186/s12889-023-15220-x |
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