Exosome-transmitted circCABIN1 promotes temozolomide resistance in glioblastoma via sustaining ErbB downstream signaling

Although temozolomide (TMZ) provides significant clinical benefit for glioblastoma (GBM), responses are limited by the emergence of acquired resistance. Here, we demonstrate that exosomal circCABIN1 secreted from TMZ-resistant cells was packaged into exosomes and then disseminated TMZ resistance of...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Guo, Qingdong, Gao, Guangxun, Cao, Zhengcong, Guan, Zhihao, Jia, Bo, Wang, Weizhong, Zhang, Kuo, Zhang, Wangqian, Wang, Shuning, Li, Weina, Hao, Qiang, Zhang, Yingqi, Li, Meng, Zhang, Wei, Gu, Jintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906870/
https://www.ncbi.nlm.nih.gov/pubmed/36755314
http://dx.doi.org/10.1186/s12951-023-01801-w

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