Identification of candidate genes and pathways associated with juvenile idiopathic arthritis by integrative transcriptome-wide association studies and mRNA expression profiles

AIM: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood, with genetic susceptibility and pathological processes such as autoimmunity and autoinflammation, but its pathogenesis is unclear. We conducted a transcriptome-wide association study (TWAS) using expr...

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Detalles Bibliográficos
Autores principales: Feng, Ruoyang, Lu, Mengnan, Yin, Chunyan, Xu, Ke, Liu, Lin, Xu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906884/
https://www.ncbi.nlm.nih.gov/pubmed/36755318
http://dx.doi.org/10.1186/s13075-023-03003-z

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