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Hi-C analysis of genomic contacts revealed karyotype abnormalities in chicken HD3 cell line

BACKGROUND: Karyotype abnormalities are frequent in immortalized continuous cell lines either transformed or derived from primary tumors. Chromosomal rearrangements can cause dramatic changes in gene expression and affect cellular phenotype and behavior during in vitro culture. Structural variations...

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Detalles Bibliográficos
Autores principales: Maslova, A., Plotnikov, V., Nuriddinov, M., Gridina, M., Fishman, V., Krasikova, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906895/
https://www.ncbi.nlm.nih.gov/pubmed/36750787
http://dx.doi.org/10.1186/s12864-023-09158-y