Hypoxia induced lactate acidosis modulates tumor microenvironment and lipid reprogramming to sustain the cancer cell survival

It is well known that solid hypoxic tumour cells oxidise glucose through glycolysis, and the end product of this pathway is fermented into lactate which accumulates in the tumour microenvironment (TME). Initially, it was proclaimed that cancer cells cannot use lactate; therefore, they dump it into t...

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Detalles Bibliográficos
Autores principales: Singh, Lakhveer, Nair, Lakshmi, Kumar, Dinesh, Arora, Mandeep Kumar, Bajaj, Sakshi, Gadewar, Manoj, Mishra, Shashank Shekher, Rath, Santosh Kumar, Dubey, Amit Kumar, Kaithwas, Gaurav, Choudhary, Manjusha, Singh, Manjari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9906992/
https://www.ncbi.nlm.nih.gov/pubmed/36761981
http://dx.doi.org/10.3389/fonc.2023.1034205

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