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Effect of Glut‐1 and HIF‐1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway

Hypoxic resistance is the main obstacle to radiotherapy for laryngeal carcinoma. Our previous study indicated that hypoxia‐inducible factor 1α (HIF‐1α) and glucose transporter 1 (Glut‐1) double knockout reduced tumour biological behaviour in laryngeal carcinoma cells. However, their radioresistance...

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Detalles Bibliográficos
Autores principales:	Bao, Yang‐Yang, Zhong, Jiang‐Tao, Shen, Li‐Fang, Dai, Li‐Bo, Zhou, Shui‐Hong, Fan, Jun, Yao, Hong‐Tian, Lu, Zhong‐Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907005/ https://www.ncbi.nlm.nih.gov/pubmed/35415942 http://dx.doi.org/10.1111/jcmm.17303

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