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Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with FGF/FGFR Aberrations Across Urinary Tract Tumors

BACKGROUND: Cyclin pathway gene alterations are frequent in urothelial tumors and may co-exist with other important aberrations, leading to therapeutic opportunities. We characterized the landscape of cyclin gene alterations in urothelial and non-urothelial urinary tract (UT) malignancies. PATIENTS...

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Detalles Bibliográficos
Autores principales: Jardim, Denis L F, Millis, Sherri Z, Ross, Jeffrey S, Lippman, Scott, Ali, Siraj M, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907036/
https://www.ncbi.nlm.nih.gov/pubmed/36082904
http://dx.doi.org/10.1093/oncolo/oyac180