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Bintrafusp Alfa: A Bifunctional Fusion Protein Targeting PD-L1 and TGF-β, in Patients with Pretreated Colorectal Cancer: Results from a Phase I Trial

Colorectal cancer (CRC) is a heterogeneous and complex disease with limited treatment options. Targeting transforming growth factor β (TGF-β) and programmed death ligand 1 pathways may enhance antitumor efficacy. Bintrafusp alfa is a first-in-class bifunctional fusion protein composed of the extrace...

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Detalles Bibliográficos
Autores principales:	Spira, Alexander, Wertheim, Michael S, Kim, Edward J, Tan, Benjamin, Lenz, Heinz-Josef, Nikolinakos, Petros, Rich, Patricia L, Jehl, Genevieve, Machl, Andreas, Ito, Rena, Gulley, James L, Kopetz, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907041/ https://www.ncbi.nlm.nih.gov/pubmed/36576431 http://dx.doi.org/10.1093/oncolo/oyac254

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