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Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
Plants have evolved the ability to distinguish between symbiotic and pathogenic microbial signals. However, potentially cooperative plant–microbe interactions often abort due to incompatible signaling. The Nodulation Specificity 1 (NS1) locus in the legume Medicago truncatula blocks tissue invasion...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907072/ https://www.ncbi.nlm.nih.gov/pubmed/36508666 http://dx.doi.org/10.1073/pnas.2214703119 |
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author | Liu, Jinge Wang, Ting Qin, Qiulin Yu, Xiaocheng Yang, Shengming Dinkins, Randy D. Kuczmog, Anett Putnoky, Péter Muszyński, Artur Griffitts, Joel S. Kereszt, Attila Zhu, Hongyan |
author_facet | Liu, Jinge Wang, Ting Qin, Qiulin Yu, Xiaocheng Yang, Shengming Dinkins, Randy D. Kuczmog, Anett Putnoky, Péter Muszyński, Artur Griffitts, Joel S. Kereszt, Attila Zhu, Hongyan |
author_sort | Liu, Jinge |
collection | PubMed |
description | Plants have evolved the ability to distinguish between symbiotic and pathogenic microbial signals. However, potentially cooperative plant–microbe interactions often abort due to incompatible signaling. The Nodulation Specificity 1 (NS1) locus in the legume Medicago truncatula blocks tissue invasion and root nodule induction by many strains of the nitrogen-fixing symbiont Sinorhizobium meliloti. Controlling this strain-specific nodulation blockade are two genes at the NS1 locus, designated NS1a and NS1b, which encode malectin-like leucine-rich repeat receptor kinases. Expression of NS1a and NS1b is induced upon inoculation by both compatible and incompatible Sinorhizobium strains and is dependent on host perception of bacterial nodulation (Nod) factors. Both presence/absence and sequence polymorphisms of the paired receptors contribute to the evolution and functional diversification of the NS1 locus. A bacterial gene, designated rns1, is required for activation of NS1-mediated nodulation restriction. rns1 encodes a type I-secreted protein and is present in approximately 50% of the nearly 250 sequenced S. meliloti strains but not found in over 60 sequenced strains from the closely related species Sinorhizobium medicae. S. meliloti strains lacking functional rns1 are able to evade NS1-mediated nodulation blockade. |
format | Online Article Text |
id | pubmed-9907072 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | National Academy of Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-99070722023-06-12 Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene Liu, Jinge Wang, Ting Qin, Qiulin Yu, Xiaocheng Yang, Shengming Dinkins, Randy D. Kuczmog, Anett Putnoky, Péter Muszyński, Artur Griffitts, Joel S. Kereszt, Attila Zhu, Hongyan Proc Natl Acad Sci U S A Biological Sciences Plants have evolved the ability to distinguish between symbiotic and pathogenic microbial signals. However, potentially cooperative plant–microbe interactions often abort due to incompatible signaling. The Nodulation Specificity 1 (NS1) locus in the legume Medicago truncatula blocks tissue invasion and root nodule induction by many strains of the nitrogen-fixing symbiont Sinorhizobium meliloti. Controlling this strain-specific nodulation blockade are two genes at the NS1 locus, designated NS1a and NS1b, which encode malectin-like leucine-rich repeat receptor kinases. Expression of NS1a and NS1b is induced upon inoculation by both compatible and incompatible Sinorhizobium strains and is dependent on host perception of bacterial nodulation (Nod) factors. Both presence/absence and sequence polymorphisms of the paired receptors contribute to the evolution and functional diversification of the NS1 locus. A bacterial gene, designated rns1, is required for activation of NS1-mediated nodulation restriction. rns1 encodes a type I-secreted protein and is present in approximately 50% of the nearly 250 sequenced S. meliloti strains but not found in over 60 sequenced strains from the closely related species Sinorhizobium medicae. S. meliloti strains lacking functional rns1 are able to evade NS1-mediated nodulation blockade. National Academy of Sciences 2022-12-12 2022-12-20 /pmc/articles/PMC9907072/ /pubmed/36508666 http://dx.doi.org/10.1073/pnas.2214703119 Text en Copyright © 2022 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Biological Sciences Liu, Jinge Wang, Ting Qin, Qiulin Yu, Xiaocheng Yang, Shengming Dinkins, Randy D. Kuczmog, Anett Putnoky, Péter Muszyński, Artur Griffitts, Joel S. Kereszt, Attila Zhu, Hongyan Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene |
title | Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene |
title_full | Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene |
title_fullStr | Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene |
title_full_unstemmed | Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene |
title_short | Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene |
title_sort | paired medicago receptors mediate broad-spectrum resistance to nodulation by sinorhizobium meliloti carrying a species-specific gene |
topic | Biological Sciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907072/ https://www.ncbi.nlm.nih.gov/pubmed/36508666 http://dx.doi.org/10.1073/pnas.2214703119 |
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