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Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene

Plants have evolved the ability to distinguish between symbiotic and pathogenic microbial signals. However, potentially cooperative plant–microbe interactions often abort due to incompatible signaling. The Nodulation Specificity 1 (NS1) locus in the legume Medicago truncatula blocks tissue invasion...

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Autores principales: Liu, Jinge, Wang, Ting, Qin, Qiulin, Yu, Xiaocheng, Yang, Shengming, Dinkins, Randy D., Kuczmog, Anett, Putnoky, Péter, Muszyński, Artur, Griffitts, Joel S., Kereszt, Attila, Zhu, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907072/
https://www.ncbi.nlm.nih.gov/pubmed/36508666
http://dx.doi.org/10.1073/pnas.2214703119
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author Liu, Jinge
Wang, Ting
Qin, Qiulin
Yu, Xiaocheng
Yang, Shengming
Dinkins, Randy D.
Kuczmog, Anett
Putnoky, Péter
Muszyński, Artur
Griffitts, Joel S.
Kereszt, Attila
Zhu, Hongyan
author_facet Liu, Jinge
Wang, Ting
Qin, Qiulin
Yu, Xiaocheng
Yang, Shengming
Dinkins, Randy D.
Kuczmog, Anett
Putnoky, Péter
Muszyński, Artur
Griffitts, Joel S.
Kereszt, Attila
Zhu, Hongyan
author_sort Liu, Jinge
collection PubMed
description Plants have evolved the ability to distinguish between symbiotic and pathogenic microbial signals. However, potentially cooperative plant–microbe interactions often abort due to incompatible signaling. The Nodulation Specificity 1 (NS1) locus in the legume Medicago truncatula blocks tissue invasion and root nodule induction by many strains of the nitrogen-fixing symbiont Sinorhizobium meliloti. Controlling this strain-specific nodulation blockade are two genes at the NS1 locus, designated NS1a and NS1b, which encode malectin-like leucine-rich repeat receptor kinases. Expression of NS1a and NS1b is induced upon inoculation by both compatible and incompatible Sinorhizobium strains and is dependent on host perception of bacterial nodulation (Nod) factors. Both presence/absence and sequence polymorphisms of the paired receptors contribute to the evolution and functional diversification of the NS1 locus. A bacterial gene, designated rns1, is required for activation of NS1-mediated nodulation restriction. rns1 encodes a type I-secreted protein and is present in approximately 50% of the nearly 250 sequenced S. meliloti strains but not found in over 60 sequenced strains from the closely related species Sinorhizobium medicae. S. meliloti strains lacking functional rns1 are able to evade NS1-mediated nodulation blockade.
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spelling pubmed-99070722023-06-12 Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene Liu, Jinge Wang, Ting Qin, Qiulin Yu, Xiaocheng Yang, Shengming Dinkins, Randy D. Kuczmog, Anett Putnoky, Péter Muszyński, Artur Griffitts, Joel S. Kereszt, Attila Zhu, Hongyan Proc Natl Acad Sci U S A Biological Sciences Plants have evolved the ability to distinguish between symbiotic and pathogenic microbial signals. However, potentially cooperative plant–microbe interactions often abort due to incompatible signaling. The Nodulation Specificity 1 (NS1) locus in the legume Medicago truncatula blocks tissue invasion and root nodule induction by many strains of the nitrogen-fixing symbiont Sinorhizobium meliloti. Controlling this strain-specific nodulation blockade are two genes at the NS1 locus, designated NS1a and NS1b, which encode malectin-like leucine-rich repeat receptor kinases. Expression of NS1a and NS1b is induced upon inoculation by both compatible and incompatible Sinorhizobium strains and is dependent on host perception of bacterial nodulation (Nod) factors. Both presence/absence and sequence polymorphisms of the paired receptors contribute to the evolution and functional diversification of the NS1 locus. A bacterial gene, designated rns1, is required for activation of NS1-mediated nodulation restriction. rns1 encodes a type I-secreted protein and is present in approximately 50% of the nearly 250 sequenced S. meliloti strains but not found in over 60 sequenced strains from the closely related species Sinorhizobium medicae. S. meliloti strains lacking functional rns1 are able to evade NS1-mediated nodulation blockade. National Academy of Sciences 2022-12-12 2022-12-20 /pmc/articles/PMC9907072/ /pubmed/36508666 http://dx.doi.org/10.1073/pnas.2214703119 Text en Copyright © 2022 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Biological Sciences
Liu, Jinge
Wang, Ting
Qin, Qiulin
Yu, Xiaocheng
Yang, Shengming
Dinkins, Randy D.
Kuczmog, Anett
Putnoky, Péter
Muszyński, Artur
Griffitts, Joel S.
Kereszt, Attila
Zhu, Hongyan
Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
title Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
title_full Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
title_fullStr Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
title_full_unstemmed Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
title_short Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene
title_sort paired medicago receptors mediate broad-spectrum resistance to nodulation by sinorhizobium meliloti carrying a species-specific gene
topic Biological Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907072/
https://www.ncbi.nlm.nih.gov/pubmed/36508666
http://dx.doi.org/10.1073/pnas.2214703119
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