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Selective involvement of UGGT variant: UGGT2 in protecting mouse embryonic fibroblasts from saturated lipid-induced ER stress
Secretory proteins and lipids are biosynthesized in the endoplasmic reticulum (ER). The “protein quality control” system (PQC) monitors glycoprotein folding and supports the elimination of terminally misfolded polypeptides. A key component of the PQC system is Uridine diphosphate glucose:glycoprotei...
Autores principales: | Hung, Hui-Hsing, Nagatsuka, Yasuko, Soldà, Tatiana, Kodali, Vamsi K., Iwabuchi, Kazuhisa, Kamiguchi, Hiroyuki, Kano, Koki, Matsuo, Ichiro, Ikeda, Kazutaka, Kaufman, Randal J., Molinari, Maurizio, Greimel, Peter, Hirabayashi, Yoshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907099/ https://www.ncbi.nlm.nih.gov/pubmed/36508673 http://dx.doi.org/10.1073/pnas.2214957119 |
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