Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2

The gut microbiota and liver cancer have a complex interaction. However, the role of gut microbiome in liver tumor initiation remains unknown. Herein, liver cancer was induced using hydrodynamic transfection of oncogenes to explore liver tumorigenesis in mice. Gut microbiota depletion promoted liver...

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Detalles Bibliográficos
Autores principales: Chen, Wen, Wen, Liang, Bao, Yingying, Tang, Zengwei, Zhao, Jianhui, Zhang, Xiaozhen, Wei, Tao, Zhang, Jian, Ma, Tao, Zhang, Qi, Zhi, Xiao, Li, Jin, Zhang, Cheng, Ni, Lei, Li, Muchun, Liang, Tingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907126/
https://www.ncbi.nlm.nih.gov/pubmed/36534812
http://dx.doi.org/10.1073/pnas.2203894119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907126/
https://www.ncbi.nlm.nih.gov/pubmed/36534812
http://dx.doi.org/10.1073/pnas.2203894119

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