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Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2
The gut microbiota and liver cancer have a complex interaction. However, the role of gut microbiome in liver tumor initiation remains unknown. Herein, liver cancer was induced using hydrodynamic transfection of oncogenes to explore liver tumorigenesis in mice. Gut microbiota depletion promoted liver...
Autores principales: | Chen, Wen, Wen, Liang, Bao, Yingying, Tang, Zengwei, Zhao, Jianhui, Zhang, Xiaozhen, Wei, Tao, Zhang, Jian, Ma, Tao, Zhang, Qi, Zhi, Xiao, Li, Jin, Zhang, Cheng, Ni, Lei, Li, Muchun, Liang, Tingbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907126/ https://www.ncbi.nlm.nih.gov/pubmed/36534812 http://dx.doi.org/10.1073/pnas.2203894119 |
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