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The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset

PURPOSE: The aim of this study was to develop a risk stratification system that predicts visual outcomes (uncorrected corrected visual acuity at one week and five weeks postoperative) in patients undergoing cataract surgery. METHODS: This was a retrospective analysis in a multitier ophthalmology net...

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Autores principales: Eckert, Kristen A, Carter, Marissa J, Das, Anthony Vipin, Lansingh, Van C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907288/
https://www.ncbi.nlm.nih.gov/pubmed/36308133
http://dx.doi.org/10.4103/ijo.IJO_1489_22
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author Eckert, Kristen A
Carter, Marissa J
Das, Anthony Vipin
Lansingh, Van C
author_facet Eckert, Kristen A
Carter, Marissa J
Das, Anthony Vipin
Lansingh, Van C
author_sort Eckert, Kristen A
collection PubMed
description PURPOSE: The aim of this study was to develop a risk stratification system that predicts visual outcomes (uncorrected corrected visual acuity at one week and five weeks postoperative) in patients undergoing cataract surgery. METHODS: This was a retrospective analysis in a multitier ophthalmology network. Data from all patients who underwent phacoemulsification or manual small-incision cataract surgery between January 2018 and December 2019 were retrieved from an electronic medical record system. There were 122,911 records; 114,172 (92.9%) had complete data included. Logistic regression analyzed unsatisfactory postoperative outcomes using a main effects model only. The final model was cross-checked using forward stepwise selection. The Hosmer–Lemeshow goodness of fit test, the Bayesian information criterion, and Nagelkerke’s R(2) assessed model fit. Dispersion was calculated from deviance and degrees of freedom and C-stat from receiving operating characteristics analysis. RESULTS: The final phacoemulsification model (n = 48,169) had a dispersion of 1.08 with a Hosmer–Lemeshow goodness of fit of 0.20, a Nagelkerke R(2) of 0.19, and a C-stat of 0.72. The final manual small-incision cataract surgery model (n = 66,003) had a dispersion of 1.05 with a Hosmer–Lemeshow goodness of fit of 0.00015, a Nagelkerke R(2) of 0.14, and a C-stat of 0.68. CONCLUSION: The phacoemulsification model had reasonable model fit; the manual small-incision cataract surgery model had poor fit and was likely missing variables. The predictive capability of these models based on a large, real-world cataract surgical dataset was suboptimal to determine which patients could benefit most from sight-restoring surgery. Appropriate patient selection for cataract surgery in developing settings should still rely on clinician thought processes, intuition, and experience, with more complex cases allocated to more experienced surgeons.
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spelling pubmed-99072882023-02-08 The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset Eckert, Kristen A Carter, Marissa J Das, Anthony Vipin Lansingh, Van C Indian J Ophthalmol Original Article PURPOSE: The aim of this study was to develop a risk stratification system that predicts visual outcomes (uncorrected corrected visual acuity at one week and five weeks postoperative) in patients undergoing cataract surgery. METHODS: This was a retrospective analysis in a multitier ophthalmology network. Data from all patients who underwent phacoemulsification or manual small-incision cataract surgery between January 2018 and December 2019 were retrieved from an electronic medical record system. There were 122,911 records; 114,172 (92.9%) had complete data included. Logistic regression analyzed unsatisfactory postoperative outcomes using a main effects model only. The final model was cross-checked using forward stepwise selection. The Hosmer–Lemeshow goodness of fit test, the Bayesian information criterion, and Nagelkerke’s R(2) assessed model fit. Dispersion was calculated from deviance and degrees of freedom and C-stat from receiving operating characteristics analysis. RESULTS: The final phacoemulsification model (n = 48,169) had a dispersion of 1.08 with a Hosmer–Lemeshow goodness of fit of 0.20, a Nagelkerke R(2) of 0.19, and a C-stat of 0.72. The final manual small-incision cataract surgery model (n = 66,003) had a dispersion of 1.05 with a Hosmer–Lemeshow goodness of fit of 0.00015, a Nagelkerke R(2) of 0.14, and a C-stat of 0.68. CONCLUSION: The phacoemulsification model had reasonable model fit; the manual small-incision cataract surgery model had poor fit and was likely missing variables. The predictive capability of these models based on a large, real-world cataract surgical dataset was suboptimal to determine which patients could benefit most from sight-restoring surgery. Appropriate patient selection for cataract surgery in developing settings should still rely on clinician thought processes, intuition, and experience, with more complex cases allocated to more experienced surgeons. Wolters Kluwer - Medknow 2022-11 2022-10-25 /pmc/articles/PMC9907288/ /pubmed/36308133 http://dx.doi.org/10.4103/ijo.IJO_1489_22 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Eckert, Kristen A
Carter, Marissa J
Das, Anthony Vipin
Lansingh, Van C
The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
title The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
title_full The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
title_fullStr The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
title_full_unstemmed The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
title_short The prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
title_sort prediction capability of a cataract surgery risk stratification model based on a large electronic medical record dataset
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907288/
https://www.ncbi.nlm.nih.gov/pubmed/36308133
http://dx.doi.org/10.4103/ijo.IJO_1489_22
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