Repurposing a Cyclin-Dependent Kinase 1 (CDK1) Mitotic Regulatory Network to Complete Terminal Differentiation in Lens Fiber Cells

PURPOSE: During lens fiber cell differentiation, organelles are removed in an ordered manner to ensure lens clarity. A critical step in this process is removal of the cell nucleus, but the mechanisms by which this occurs are unclear. In this study, we investigate the role of a cyclin-dependent kinas...

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Detalles Bibliográficos
Autores principales: Taylor, Allen, Gu, Yumei, Chang, Min-Lee, Yang, Wenxin, Francisco, Sarah, Rowan, Sheldon, Bejarano, Eloy, Pruitt, Steven, Zhu, Liang, Weiss, Grant, Brennan, Lisa, Kantorow, Marc, Whitcomb, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907369/
https://www.ncbi.nlm.nih.gov/pubmed/36734965
http://dx.doi.org/10.1167/iovs.64.2.6

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