The Impact of Extended Treatment With Artemether-lumefantrine on Antimalarial Exposure and Reinfection Risks in Ugandan Children With Uncomplicated Malaria: A Randomized Controlled Trial

BACKGROUND: Artemether-lumefantrine (AL) is the most widely used artemisinin-based combination therapy in Sub-Saharan Africa and is threatened by the emergence of artemisinin resistance. Dosing is suboptimal in young children. We hypothesized that extending AL duration will improve exposure and redu...

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Detalles Bibliográficos
Autores principales: Whalen, Meghan E, Kajubi, Richard, Goodwin, Justin, Orukan, Francis, Colt, McKenzie, Huang, Liusheng, Richards, Kacey, Wang, Kaicheng, Li, Fangyong, Mwebaza, Norah, Aweeka, Francesca T, Parikh, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907485/
https://www.ncbi.nlm.nih.gov/pubmed/36130191
http://dx.doi.org/10.1093/cid/ciac783

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