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Pharmacokinetic-Pharmacodynamic Determinants of Clinical Outcomes for Rifampin-Resistant Tuberculosis: A Multisite Prospective Cohort Study
BACKGROUND: Rifampin-resistant and/or multidrug-resistant tuberculosis (RR/MDR-TB) treatment requires multiple drugs, and outcomes remain suboptimal. Some drugs are associated with improved outcome. It is unknown whether particular pharmacokinetic-pharmacodynamic relationships predict outcome. METHO...
Autores principales: | Heysell, Scott K, Mpagama, Stellah G, Ogarkov, Oleg B, Conaway, Mark, Ahmed, Shahriar, Zhdanova, Svetlana, Pholwat, Suporn, Alshaer, Mohammad H, Chongolo, Anna M, Mujaga, Buliga, Sariko, Margaretha, Saba, Sabrina, Rahman, S M Mazidur, Uddin, Mohammad Khaja Mafij, Suzdalnitsky, Alexey, Moiseeva, Elena, Zorkaltseva, Elena, Koshcheyev, Mikhail, Vitko, Serhiy, Mmbaga, Blandina T, Kibiki, Gibson S, Pasipanodya, Jotam G, Peloquin, Charles A, Banu, Sayera, Houpt, Eric R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907514/ https://www.ncbi.nlm.nih.gov/pubmed/35731948 http://dx.doi.org/10.1093/cid/ciac511 |
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