Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus

We screened 65 longitudinally collected nasal swab samples from 31 children aged 0–16 years who were positive for severe acute respiratory syndrome coronavirus 2 Omicron BA.1. By day 7 after onset of symptoms, 48% of children remained positive by rapid antigen test. In a sample subset, we found 100%...

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Autores principales: Lohse, Zoe M, Shapiro, Jerne J, Lednicky, John A, Cash, Melanie N, Jun, Inyoung, Mavian, Carla N, Tagliamonte, Massimiliano S, Saleem, Cyrus, Yang, Yang, Nelson, Eric J, Salemi, Marco, Ryan, Kathleen A, Morris, J Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907546/
https://www.ncbi.nlm.nih.gov/pubmed/36029095
http://dx.doi.org/10.1093/cid/ciac693
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author Lohse, Zoe M
Shapiro, Jerne J
Lednicky, John A
Cash, Melanie N
Jun, Inyoung
Mavian, Carla N
Tagliamonte, Massimiliano S
Saleem, Cyrus
Yang, Yang
Nelson, Eric J
Salemi, Marco
Ryan, Kathleen A
Morris, J Glenn
author_facet Lohse, Zoe M
Shapiro, Jerne J
Lednicky, John A
Cash, Melanie N
Jun, Inyoung
Mavian, Carla N
Tagliamonte, Massimiliano S
Saleem, Cyrus
Yang, Yang
Nelson, Eric J
Salemi, Marco
Ryan, Kathleen A
Morris, J Glenn
author_sort Lohse, Zoe M
collection PubMed
description We screened 65 longitudinally collected nasal swab samples from 31 children aged 0–16 years who were positive for severe acute respiratory syndrome coronavirus 2 Omicron BA.1. By day 7 after onset of symptoms, 48% of children remained positive by rapid antigen test. In a sample subset, we found 100% correlation between antigen test results and virus culture.
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spelling pubmed-99075462023-02-09 Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus Lohse, Zoe M Shapiro, Jerne J Lednicky, John A Cash, Melanie N Jun, Inyoung Mavian, Carla N Tagliamonte, Massimiliano S Saleem, Cyrus Yang, Yang Nelson, Eric J Salemi, Marco Ryan, Kathleen A Morris, J Glenn Clin Infect Dis Brief Report We screened 65 longitudinally collected nasal swab samples from 31 children aged 0–16 years who were positive for severe acute respiratory syndrome coronavirus 2 Omicron BA.1. By day 7 after onset of symptoms, 48% of children remained positive by rapid antigen test. In a sample subset, we found 100% correlation between antigen test results and virus culture. Oxford University Press 2022-08-27 /pmc/articles/PMC9907546/ /pubmed/36029095 http://dx.doi.org/10.1093/cid/ciac693 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Lohse, Zoe M
Shapiro, Jerne J
Lednicky, John A
Cash, Melanie N
Jun, Inyoung
Mavian, Carla N
Tagliamonte, Massimiliano S
Saleem, Cyrus
Yang, Yang
Nelson, Eric J
Salemi, Marco
Ryan, Kathleen A
Morris, J Glenn
Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus
title Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus
title_full Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus
title_fullStr Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus
title_full_unstemmed Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus
title_short Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus
title_sort persistence of severe acute respiratory syndrome coronavirus 2 omicron variant in children and utility of rapid antigen testing as an indicator of culturable virus
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907546/
https://www.ncbi.nlm.nih.gov/pubmed/36029095
http://dx.doi.org/10.1093/cid/ciac693
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