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A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft

Dermatofibrosarcoma protuberans (DFSP) is an overall rare malignancy yet is one of the most common cutaneous sarcomas. The diagnosis of DFSP is typically made following histopathologic examination of the lesion, classically revealing a storiform pattern of spindle cells with elongated nuclei infiltr...

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Autores principales: Nawrocki, Shiri, Rubin, Alexandra, Srivastava, Radhika, Chamorro, Paola, Rao, Babar K., Wassef, Cindy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907619/
https://www.ncbi.nlm.nih.gov/pubmed/34751469
http://dx.doi.org/10.1111/srt.13117
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author Nawrocki, Shiri
Rubin, Alexandra
Srivastava, Radhika
Chamorro, Paola
Rao, Babar K.
Wassef, Cindy M.
author_facet Nawrocki, Shiri
Rubin, Alexandra
Srivastava, Radhika
Chamorro, Paola
Rao, Babar K.
Wassef, Cindy M.
author_sort Nawrocki, Shiri
collection PubMed
description Dermatofibrosarcoma protuberans (DFSP) is an overall rare malignancy yet is one of the most common cutaneous sarcomas. The diagnosis of DFSP is typically made following histopathologic examination of the lesion, classically revealing a storiform pattern of spindle cells with elongated nuclei infiltrating the dermis and subcutis. Surgical excision is the standard treatment. Local recurrence is estimated to occur in 20−50% of cases, thus frequent postsurgical monitoring is required. Noninvasive imaging modalities offer a potential alternative to multiple repeat biopsies. We report the first case where reflectance confocal microscopy accompanied clinical examination in monitoring for DFSP recurrence postsurgical excision.
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spelling pubmed-99076192023-04-13 A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft Nawrocki, Shiri Rubin, Alexandra Srivastava, Radhika Chamorro, Paola Rao, Babar K. Wassef, Cindy M. Skin Res Technol Letters Dermatofibrosarcoma protuberans (DFSP) is an overall rare malignancy yet is one of the most common cutaneous sarcomas. The diagnosis of DFSP is typically made following histopathologic examination of the lesion, classically revealing a storiform pattern of spindle cells with elongated nuclei infiltrating the dermis and subcutis. Surgical excision is the standard treatment. Local recurrence is estimated to occur in 20−50% of cases, thus frequent postsurgical monitoring is required. Noninvasive imaging modalities offer a potential alternative to multiple repeat biopsies. We report the first case where reflectance confocal microscopy accompanied clinical examination in monitoring for DFSP recurrence postsurgical excision. John Wiley and Sons Inc. 2021-11-09 /pmc/articles/PMC9907619/ /pubmed/34751469 http://dx.doi.org/10.1111/srt.13117 Text en © 2021 The Authors. Skin Research and Technology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letters
Nawrocki, Shiri
Rubin, Alexandra
Srivastava, Radhika
Chamorro, Paola
Rao, Babar K.
Wassef, Cindy M.
A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
title A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
title_full A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
title_fullStr A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
title_full_unstemmed A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
title_short A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
title_sort case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
topic Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907619/
https://www.ncbi.nlm.nih.gov/pubmed/34751469
http://dx.doi.org/10.1111/srt.13117
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