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A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft
Dermatofibrosarcoma protuberans (DFSP) is an overall rare malignancy yet is one of the most common cutaneous sarcomas. The diagnosis of DFSP is typically made following histopathologic examination of the lesion, classically revealing a storiform pattern of spindle cells with elongated nuclei infiltr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907619/ https://www.ncbi.nlm.nih.gov/pubmed/34751469 http://dx.doi.org/10.1111/srt.13117 |
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author | Nawrocki, Shiri Rubin, Alexandra Srivastava, Radhika Chamorro, Paola Rao, Babar K. Wassef, Cindy M. |
author_facet | Nawrocki, Shiri Rubin, Alexandra Srivastava, Radhika Chamorro, Paola Rao, Babar K. Wassef, Cindy M. |
author_sort | Nawrocki, Shiri |
collection | PubMed |
description | Dermatofibrosarcoma protuberans (DFSP) is an overall rare malignancy yet is one of the most common cutaneous sarcomas. The diagnosis of DFSP is typically made following histopathologic examination of the lesion, classically revealing a storiform pattern of spindle cells with elongated nuclei infiltrating the dermis and subcutis. Surgical excision is the standard treatment. Local recurrence is estimated to occur in 20−50% of cases, thus frequent postsurgical monitoring is required. Noninvasive imaging modalities offer a potential alternative to multiple repeat biopsies. We report the first case where reflectance confocal microscopy accompanied clinical examination in monitoring for DFSP recurrence postsurgical excision. |
format | Online Article Text |
id | pubmed-9907619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99076192023-04-13 A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft Nawrocki, Shiri Rubin, Alexandra Srivastava, Radhika Chamorro, Paola Rao, Babar K. Wassef, Cindy M. Skin Res Technol Letters Dermatofibrosarcoma protuberans (DFSP) is an overall rare malignancy yet is one of the most common cutaneous sarcomas. The diagnosis of DFSP is typically made following histopathologic examination of the lesion, classically revealing a storiform pattern of spindle cells with elongated nuclei infiltrating the dermis and subcutis. Surgical excision is the standard treatment. Local recurrence is estimated to occur in 20−50% of cases, thus frequent postsurgical monitoring is required. Noninvasive imaging modalities offer a potential alternative to multiple repeat biopsies. We report the first case where reflectance confocal microscopy accompanied clinical examination in monitoring for DFSP recurrence postsurgical excision. John Wiley and Sons Inc. 2021-11-09 /pmc/articles/PMC9907619/ /pubmed/34751469 http://dx.doi.org/10.1111/srt.13117 Text en © 2021 The Authors. Skin Research and Technology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Letters Nawrocki, Shiri Rubin, Alexandra Srivastava, Radhika Chamorro, Paola Rao, Babar K. Wassef, Cindy M. A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
title | A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
title_full | A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
title_fullStr | A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
title_full_unstemmed | A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
title_short | A case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
title_sort | case of dermatofibrosarcoma protuberans and reflectance confocal microscopy of a post‐surgical skin graft |
topic | Letters |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907619/ https://www.ncbi.nlm.nih.gov/pubmed/34751469 http://dx.doi.org/10.1111/srt.13117 |
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