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Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin
BACKGROUND: Dry skin can trigger eczema that affects >10% of the US population. Dressing films have been developed to improve diseased skin, but there is limited knowledge about their effects, especially for dry skin‐related symptoms. We developed an electrospinning method that creates a coating...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907623/ https://www.ncbi.nlm.nih.gov/pubmed/35411972 http://dx.doi.org/10.1111/srt.13149 |
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author | Gabe, Yu Uchiyama, Masayuki Sasaoka, Shun Amari, Naomi Imai, Asuka Hachiya, Akira Kiyomine, Akira |
author_facet | Gabe, Yu Uchiyama, Masayuki Sasaoka, Shun Amari, Naomi Imai, Asuka Hachiya, Akira Kiyomine, Akira |
author_sort | Gabe, Yu |
collection | PubMed |
description | BACKGROUND: Dry skin can trigger eczema that affects >10% of the US population. Dressing films have been developed to improve diseased skin, but there is limited knowledge about their effects, especially for dry skin‐related symptoms. We developed an electrospinning method that creates a coating film, called a fine fiber (FF) film, characterized by the production of a transparent, thin, flexible, and adherent membrane on the skin surface. OBJECTIVE: The aim of this pilot study was to examine the effects of the FF film on dry skin. METHODS: Three treatments (lotion only, lotion with the FF film, and lotion with an alternative film) were designed to treat subjects with rough skin on their lower legs. Twenty‐four females were enrolled and used either a water‐based lotion U or a petrolatum‐based lotion P and the FF film for 2 weeks followed by a regression phase for 1 week. Skin hydration and roughness scores were assessed as were the subjects’ perceptions of the effects. RESULTS: When the FF film was applied with lotion U, skin hydration was significantly improved even after 1 week, accompanied by a significant improvement of skin roughness and an increase in skin hydration by the end of the regression phase. An evaluation of moisture permeability suggested that the FF film, especially with lotion U, performed as a semipermeable membrane with optimal moisture healing effects on dry skin. CONCLUSION: The FF film together with a water‐based lotion is a promising treatment to quickly improve dry skin conditions. |
format | Online Article Text |
id | pubmed-9907623 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99076232023-04-13 Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin Gabe, Yu Uchiyama, Masayuki Sasaoka, Shun Amari, Naomi Imai, Asuka Hachiya, Akira Kiyomine, Akira Skin Res Technol Original Articles BACKGROUND: Dry skin can trigger eczema that affects >10% of the US population. Dressing films have been developed to improve diseased skin, but there is limited knowledge about their effects, especially for dry skin‐related symptoms. We developed an electrospinning method that creates a coating film, called a fine fiber (FF) film, characterized by the production of a transparent, thin, flexible, and adherent membrane on the skin surface. OBJECTIVE: The aim of this pilot study was to examine the effects of the FF film on dry skin. METHODS: Three treatments (lotion only, lotion with the FF film, and lotion with an alternative film) were designed to treat subjects with rough skin on their lower legs. Twenty‐four females were enrolled and used either a water‐based lotion U or a petrolatum‐based lotion P and the FF film for 2 weeks followed by a regression phase for 1 week. Skin hydration and roughness scores were assessed as were the subjects’ perceptions of the effects. RESULTS: When the FF film was applied with lotion U, skin hydration was significantly improved even after 1 week, accompanied by a significant improvement of skin roughness and an increase in skin hydration by the end of the regression phase. An evaluation of moisture permeability suggested that the FF film, especially with lotion U, performed as a semipermeable membrane with optimal moisture healing effects on dry skin. CONCLUSION: The FF film together with a water‐based lotion is a promising treatment to quickly improve dry skin conditions. John Wiley and Sons Inc. 2022-04-12 /pmc/articles/PMC9907623/ /pubmed/35411972 http://dx.doi.org/10.1111/srt.13149 Text en © 2022 The Authors. Skin Research and Technology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Gabe, Yu Uchiyama, Masayuki Sasaoka, Shun Amari, Naomi Imai, Asuka Hachiya, Akira Kiyomine, Akira Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
title | Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
title_full | Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
title_fullStr | Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
title_full_unstemmed | Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
title_short | Efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
title_sort | efficacy of a fine fiber film applied with a water‐based lotion to improve dry skin |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907623/ https://www.ncbi.nlm.nih.gov/pubmed/35411972 http://dx.doi.org/10.1111/srt.13149 |
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