Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT

Brown fat activation with increased radiotracer localization on FDG PET/CT studies is a well-known phenomenon. Activated brown adipose tissue (BAT) is usually seen in the supraclavicular region, but also in paraspinal and rarely in upper abdominal fat. Ours is a unique case of atypically intense, mu...

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Autores principales: Brahmbhatt, Pavan, Ataei, Fatemeh, Parent, Ephraim E., Sharma, Akash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907682/
https://www.ncbi.nlm.nih.gov/pubmed/36723882
http://dx.doi.org/10.1097/RLU.0000000000004520
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author Brahmbhatt, Pavan
Ataei, Fatemeh
Parent, Ephraim E.
Sharma, Akash
author_facet Brahmbhatt, Pavan
Ataei, Fatemeh
Parent, Ephraim E.
Sharma, Akash
author_sort Brahmbhatt, Pavan
collection PubMed
description Brown fat activation with increased radiotracer localization on FDG PET/CT studies is a well-known phenomenon. Activated brown adipose tissue (BAT) is usually seen in the supraclavicular region, but also in paraspinal and rarely in upper abdominal fat. Ours is a unique case of atypically intense, multilobular FDG uptake in activated BAT. Chart review revealed that the patient was receiving mirabegron, a known activator of brown fat. Methods of reducing brown fat uptake are known, but little information is reported on pharmacologic causes of increased uptake. Factors increasing FDG uptake in BAT should also be considered when interpreting PET/CT studies.
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spelling pubmed-99076822023-02-14 Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT Brahmbhatt, Pavan Ataei, Fatemeh Parent, Ephraim E. Sharma, Akash Clin Nucl Med Interesting Images Brown fat activation with increased radiotracer localization on FDG PET/CT studies is a well-known phenomenon. Activated brown adipose tissue (BAT) is usually seen in the supraclavicular region, but also in paraspinal and rarely in upper abdominal fat. Ours is a unique case of atypically intense, multilobular FDG uptake in activated BAT. Chart review revealed that the patient was receiving mirabegron, a known activator of brown fat. Methods of reducing brown fat uptake are known, but little information is reported on pharmacologic causes of increased uptake. Factors increasing FDG uptake in BAT should also be considered when interpreting PET/CT studies. Lippincott Williams & Wilkins 2023-03 2023-01-10 /pmc/articles/PMC9907682/ /pubmed/36723882 http://dx.doi.org/10.1097/RLU.0000000000004520 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Interesting Images
Brahmbhatt, Pavan
Ataei, Fatemeh
Parent, Ephraim E.
Sharma, Akash
Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT
title Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT
title_full Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT
title_fullStr Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT
title_full_unstemmed Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT
title_short Atypically Intense Pharmacologically Induced Brown Fat Activation on FDG PET/CT
title_sort atypically intense pharmacologically induced brown fat activation on fdg pet/ct
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907682/
https://www.ncbi.nlm.nih.gov/pubmed/36723882
http://dx.doi.org/10.1097/RLU.0000000000004520
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