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AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs
Macroautophagy/autophagy is an intracellular degradation process central to cellular homeostasis and defense against pathogens in eukaryotic cells. Regulation of autophagy relies on hierarchical binding of autophagy cargo receptors and adaptors to ATG8/LC3 protein family members. Interactions with A...
Autores principales: | Ibrahim, Tarhan, Khandare, Virendrasinh, Mirkin, Federico Gabriel, Tumtas, Yasin, Bubeck, Doryen, Bozkurt, Tolga O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907853/ https://www.ncbi.nlm.nih.gov/pubmed/36753519 http://dx.doi.org/10.1371/journal.pbio.3001962 |
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