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AlphaFold2-multimer guided high-accuracy prediction of typical and atypical ATG8-binding motifs

Macroautophagy/autophagy is an intracellular degradation process central to cellular homeostasis and defense against pathogens in eukaryotic cells. Regulation of autophagy relies on hierarchical binding of autophagy cargo receptors and adaptors to ATG8/LC3 protein family members. Interactions with A...

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Detalles Bibliográficos
Autores principales: Ibrahim, Tarhan, Khandare, Virendrasinh, Mirkin, Federico Gabriel, Tumtas, Yasin, Bubeck, Doryen, Bozkurt, Tolga O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907853/
https://www.ncbi.nlm.nih.gov/pubmed/36753519
http://dx.doi.org/10.1371/journal.pbio.3001962

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