The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements

As a class of essential enzymes in protein translation, aminoacyl–transfer RNA (tRNA) synthetases (aaRSs) are organized into two classes of 10 enzymes each, based on two conserved active site architectures. The (αβ)(2) glycyl-tRNA synthetase (GlyRS) in many bacteria is an orphan aaRS whose sequence...

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Detalles Bibliográficos
Autores principales: Han, Lu, Luo, Zhiteng, Ju, Yingchen, Chen, Bingyi, Zou, Taotao, Wang, Junjian, Xu, Jun, Gu, Qiong, Yang, Xiang-Lei, Schimmel, Paul, Zhou, Huihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908026/
https://www.ncbi.nlm.nih.gov/pubmed/36753552
http://dx.doi.org/10.1126/sciadv.adf1027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908026/
https://www.ncbi.nlm.nih.gov/pubmed/36753552
http://dx.doi.org/10.1126/sciadv.adf1027

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